hou po 厚朴

hou po 厚朴, hòu pò 厚樸, chuan pò 川 樸
Pharmaceutical name英文药名：
Cortex Magnoliae Officinalis
Latin botanical name拉丁植物学名：
Magnolia officinalis Rehd. et Wils. ssp. biloba（Rehd. et Wils.）Law
Magnolia  obovata, Thunb. (produced in Japan)
Magnolia fargesii
Magnolia biloba (Rehd． Et Wils.) Cheng (凹葉厚朴)
Common Name英文名：
magnolia bark
Other Names别名：
shan he hua (山荷花)﹐ he hua po (荷厚樸) , he hua mu lan  (荷花木蘭)
Distribution産地：
Sichuan, Hunan, Hubei, Zhejian, Guangxi, Jiangxi. Sichuan, Guizhou, Yunnan, Shaanxi, Anhui, Gansu provinces of China.
Magnolia biloba (Rehd． Et Wils.) Cheng is distributed in Zhejiang, Jiangxi, Anhui, Guangxi provinces. Mainly produced in Sichuan, Hubei, Zhejiang, Guizhou, and Hunan provinces of China.
厚朴分布浙江，廣西，江西，湖南，湖北，四川，貴州，雲南，陝西，安徽，甘肅等地。
凹葉厚朴分布浙江，江西，安徽，廣西等地。主產四川，湖北，浙江，貴州，湖南。
Properties (characteristics)性味：
bitter, acrid warm and aromatic
味苦，辛﹐温，香。
Channels (meridians) entered歸經：
large intestine, lung, spleen, stomach
大腸，肺，脾，胃。
Actions & Indications主治：
transform phlegm and rids of dampness and stagnation in spleen and stomach indigestion, flatulence, loss of appetite, vomiting, diarrhea and constipation.
具有燥濕消痰，下氣除滿之功能。
用於濕滯傷中，脘痞吐瀉，食積氣滯，腹脹便秘，痰飲喘咳。
Medical Function藥理：
the decoction in test tubes show that it had strong inhibition of Staphylococcus aureus
relaxing skeletal muscle effect
improves digestion, inhibits pain and sedative effect
anti-coagulation of platelets
anti-cancer
induces apoptosis in acute myelogenous leukemia (AML) cells.
induces apoptosis in B-cell chronic lymphocytic leukemia (B-CLL)
本品煎劑在試管中，對金黃色葡萄球菌有很強的抑制作用。
鬆弛骨骼肌作用﹐
健胃﹐鎮痛﹐鎮靜，
抗血小板凝集，
抗癌，
和厚朴酚可使急性颗粒白血病细胞凋亡，
和厚朴酚可使慢性淋巴细胞白血病细胞凋亡。
Chemical ingredients化學成份：
1. Magnolol 厚朴酚, tetrahydromagnolol, isomagnolol, honokiol 和厚朴酚, Randainal, syringaresinol, syringaresinol 4-O-Beta-D-glucopyranoside, 6'-O-methyl-honokiol, magnaldehyde, B, C; magnolignan A, B, C, D, E.
2. Magnatriol B, magnaldehyde #, #,; Randaiol.
3. Magnolignan F, G, H, I.
4. Piperitylmagnolol, pipertylhonokiol, dipiperitylmagnolol, bornylmagnolol.
5. Eudesmol, alpha-pinene, Beta-pinene, p-cymene; 1, 4-cineol; alpha-limonene, carene-3, linalool, beta-bisabolene, terpinen-4-ol, alpha-terpineol, bornyl acetate, linalyl acetate, caryophyllene, alphe-humulene, alphe-copaene, aromadendrene, alloaromadendrene, alpha-cedrene, elemeol, Globulol, alpha-santalol, butylidenecyclohexane, guaiol, beta-guaiene, Cardinol, guaiazulene.
6. Magnocurarine
7. Sinapic aldehyde, 1-(4-hydroxy-3-methoxyphenyl) -2 -(4_ (W-hydroxypropyl) - 2-methoxyphenoxy) propane-1, 3-diol.
Dosage用量：
3- 12 g;
hou pu hua (flower):3-6 g
Samples of formulae:
處方舉例：
hou pu san wu tang 厚樸三物湯
da cheng tang 大成湯 (外科正宗)
Modern Research现代研究：
One of the active chemicals. honokiol, can cause B-cells of lymphocytic leukemia into apoptosis. Honokiol does not ge destroyed by the digestive system readily. It can be effective in decoction.
厚朴酚能使到淋巴白學病之B细胞凋亡。厚朴酚不易被消化系统破壞，所以厚朴用於湯剤會有效。
Cautions禁忌：
Use caution during pregnancy.
It antagonizes ze xie and han shui shi (寒 水 石 ).
Large dosages and/or long term usage can be toxic to kidneys.
懷孕期間，小心應用。反澤 蘭或寒水石。大劑量或長期服用可能對腎臟有毒。