Pharmaceutical name 藥名 ﹕Radix Bupleuri
Biological name 拉丁學名 ﹕Bupleurum chinense DC. (north chai hu) / Bupleurum scorzonerifolium Wild.(south chai hu or xi chai hu or ruan chai hu)
Common Name 英文 ﹕thorowax root, hare's ear root
Other names 別名:
chun chai hu (literally spring chai hu)春柴胡, chai hu 柴胡, di xun 地熏, zi hu 茈胡, shan cai 山菜, 茹草, 柴草, 軟柴胡, 硬柴胡, 芽胡, 芽柴胡, 春胡, 南胡, 才胡, 地薰, 芸蒿
1. Bupleurum chinense: bei chai hu (literally northern chai hu), ying chai hu (literally hard chai hu)
2. Bupleurum scorzonerifolium: nan chai hu (literally southern chai hu), xi chai hu (literally thin chai hu), ruan chai hu (literally soft chai hu)
3. 北柴胡(硬柴胡 [Bupleurum chinense]),
4. 南柴胡(細柴胡,軟柴胡[Bupleurum scorzonerifolium])
Distribution 分佈 ﹕
1. Bupleurum chinense DC. (north chai hu) is mainly produced in Liaoning, Gansu, Hebei, Henan.
2. Bupleurum scorzonerifolium Wild.(south chai hu or xi chai hu or ruan chai hu) is mainly produced in Hubei, Jiangsu, Sichuan.
3. 北柴胡(硬柴胡)主產 遼 寧 、甘 肅 、河北、河南。
4. 南柴胡(細柴胡,軟柴胡)主產 湖北、江 蘇 、四川。
Properties (characteristics) 性味 ﹕bitter, slightly cold. 苦﹐略寒。
Channels (meridians) entered 歸經 ﹕liver, gall bladder, pericardium, triple fire
Actions & Indications 主治 ﹕
to disperse heat and fever, improve yang. For cold and influenza, alternating chill and fever, malaria, fullness in chest and rib cage, irregular menses, prolapse of uterus, and prolapse of rectum.
疏散 退熱,升陽舒肝。用于感冒發熱, 寒熱往來, 瘧疾, 肝鬱氣滞, 胸胁胀痛, 脱肛, 子宫脱垂, 月經不不調。
Medical Function 藥理﹕
1. calming effect on CNS
2. pain relieving,
3. antipyretic, reducing heat
4. anti inflammation
5. effect on immune system
6. effect on digestive system
7. effect on heart and blood vessels
8. effect on excretion of urine﹕small amount improves urination and large amount does not have the effect
9.anti tumor
10.anti bacteria, virus, and amoeba
11.effect on metabolism
12.improves liver function
1. 鎮靜
2. 解熱
3. 鎮痛
4. 抗炎
5. 促進免疫功能
6. 消化系統作用
7. 心血管作用
8. 抗癌作用
9. 利尿作用﹕小量有利尿作用﹔大劑量無此作用
10.抗菌及抗流感病毒
11.新陳代謝作用
12.改善肝功能
Chemical ingredients 化學成份 ﹕
1. Vaporizing oils: 2-methyl cyclopentaone, limonene, myrcene, (+)-carvone, trans-tarved carveol, pulegone, myrtenol, α-terpineol, linalool, geraniol, n-tridecane, (E) - geranylacetone, α-cubebene, humulene, trans-caryophyllene, longifolene, nootkatone, hexadecanoic acid, hexahydrofarnesylacetone, pentanic acid, caproic acid, heptylic acid, 2-heptenic acid, caprylic acid, 2-octenic acid, pelargonic acid, 2-nonenic acid, phenol, O-methoxy phenol, gamma-heptalactone, gamma-decalactone, eugenol, gamma-undecalactone, methyl phenol, ethyl phenol, thymol, messoia lactone, vanillin acetate.
β-terpinene, limonene, β-fenchene, pulegone, isoborneol, β-terpineol, α-copaene, humulene, a-farnesene, aromadendrene, cis-caryophyllene, trans-caryophyllene, β-elemene, gamma-muurolene, patchoulane, nootkatone, ledol.
2. Saponins: Saikosaponin, saikogenin, longispinogenin.
3. Organic acids: Oleic acid, linolenic acid, palmitic acid, steaeric acid, lignoceric acid.
4. Ethanol group: α-spinasterol, delta7-stimasteneol, delta22-stigmaastenol, stigmasterol, adonitol, bupleuromol.
5. Others: Angelicin, calcium, potassium, aluminum
Dosage 用量 ﹕
3 to 12 g
3~12 克 。
Modern Application現代應用﹕
1. to reduce fever
2. cough
3. viral infection of the liver
4. to lower ALT and AST : [6]
5. for high lipids of blood
6. globus hystericus
1. 解熱
2. 止咳嗽
3. 肝臟病毒感染
4. 降肝臟 ALT 與 AST
5. 高血脂
6. 梅核氣
Cautions 警語:
It is mildly toxic. Not for use in cases of yin deficiency cough or headache due to ascending liver fire.
Overdose causes headaches, dizziness, vomiting, tremors, gastroenteritis, and pathogenic erections.
There were report of cases of mortality of broncho-interstitial pneumonia suspected were being caused by the combined use of chai hu formulae and interferon.
Large dosages and/or long term usage can be toxic to kidneys.
有將柴胡製劑與干擾素併用,引發間質性肺炎而死亡的案例。
大劑量或長期服用可能對腎臟有毒。
by: Joe Hing Kwok Chu
Medical Records: JUN 2000 suffered from obstructive hydrocephalus (Taichung Veterans General Hospital)/ 4 SEP 2003 Taichung Veterans General Hospital confirmed suspect subarachnoid cyst 34×12mm(inference 30×10×10mm at 28 AUG)/ 29 SEP 2003 Chang Gung Memorial Hospital Linkou Branch surgery to remove the brain tumor, diameter of 47.5mm/ FEB 2007 benign neoplasm of brain/ DEC 2010 China Medical University Hospital Cancer Center for the Chinese medical treatment.
Status
Current conditions ICD-9-CM:
2003
225.0 BENIGN NEOPLASM OF BRAIN
345.90 UNSPECIFIED EPILEPSY WITHOUT MENTION OF INTRACTABLE EPILEPSY
2010
225.0 BENIGN NEOPLASM OF BRAIN
345.90 UNSPECIFIED EPILEPSY WITHOUT MENTION OF INTRACTABLE EPILEPSY
2012
225.0 BENIGN NEOPLASM OF BRAIN
345.90 UNSPECIFIED EPILEPSY WITHOUT MENTION OF INTRACTABLE EPILEPSY
375.15 TEAR FILM INSUFFICIENCY,UNSPECIFIED
367.89 OTHER DISORDERS OF REFRACTION AND ACCOMMODATION
377.61 ASSOCIATED WITH NEOPLASMS
729.1 MYALGIA AND MYOSITIS, UNSPECIFIED
719.39 PALINDROMIC RHEUMATISM,MULTIPLE SITES
680.0 CARBUNCLE AND FURUNCLE, FACE
378.41 ESOPHORIA
311 DEPRESSIVE DISORDER, NOT ELSEWHERE CLASSIFIED
523.8 OTHER PERIODONTAL DISEASES(PERIODONTAL POCKET,GINGIVAL POLYP)
681.02 ONYCHIA AND PARONYCHIA OF FINGER
2013
225.0 BENIGN NEOPLASM OF BRAIN
345.90 UNSPECIFIED EPILEPSY WITHOUT MENTION OF INTRACTABLE EPILEPSY
704.8 OTHER DISEASES OF HAIR AND HAIR FOLLICLES
706.1 OTHER ACNE
444.22 ARTERIAL EMBOLISM AND THROMBOSIS OF LOWER EXTREMITY
375.15 TEAR FILM INSUFFICIENCY,UNSPECIFIED
367.89 OTHER DISORDERS OF REFRACTION AND ACCOMMODATION
377.61 ASSOCIATED WITH NEOPLASMS
378.41 ESOPHORIA
728.85 (728.850) SPASM OF MUSCLE
353.4 LUMBOSACRAL ROOT LESIONS,NOT ELSEWHERE CLASSIFIED
780.52 (780.520) OTHER INSOMNIA
788.43 NOCTURIA
2014
225.0 BENIGN NEOPLASM OF BRAIN
345.90 UNSPECIFIED EPILEPSY WITHOUT MENTION OF INTRACTABLE EPILEPSY
374.05 TRICHIASIS WITHOUT ENTROPION
372.72 CONJUNCTIVAL HEMORRHAGE
375.15 TEAR FILM INSUFFICIENCY,UNSPECIFIED
367.89 OTHER DISORDERS OF REFRACTION AND ACCOMMODATION
377.61 ASSOCIATED WITH NEOPLASMS
378.41 ESOPHORIA
2015
225.0 BENIGN NEOPLASM OF BRAIN
345.90 UNSPECIFIED EPILEPSY WITHOUT MENTION OF INTRACTABLE EPILEPSY
705.83 HIDRADENITIS
698.8 OTHER PRURITIC CONDITIONS
686.9 UNSPECIFIED LOCAL INFECTIONS OF SKIN AND SUBCUTANEOUS TISSUE
686.09 OTHER PYODERMA
272.0 PURE HYPERCHOLESTEROLAEMIA (FAMILIAL HYPERCHOLESTESTEROLEMIA)
729.1 MYALGIA AND MYOSITIS, UNSPECIFIED
719.39 PALINDROMIC RHEUMATISM,MULTIPLE SITES
377.61 ASSOCIATED WITH NEOPLASMS
311 DEPRESSIVE DISORDER, NOT ELSEWHERE CLASSIFIED
307.48 REPETITIVE INTRUSIONS OF SLEEP
705.81 DYSHIDROSIS
372.72 CONJUNCTIVAL HEMORRHAGE
680.2 CARBUNCLE AND FURUNCLE, TRUNK
523.3 ACUTE PERIODONTITIS(ACUTE PERICORONITIS)
Current conditions ICD-10-CM:
2016
E780 Pure hypercholesterolemia
G40.909 Epilepsy, unspecified, not intractable, without status epilepticus
L301 Dyshidrosis [pompholyx]
F32.9 Major depressive disorder, single episode, unspecified
D33.2 Benign neoplasm of brain, unspecified
H04.123 Dry eye syndrome of bilateral lacrimal glands
H47.529 Disorders of visual pathways in (due to) neoplasm, unspecified side
H02.052 Trichiasis without entropian right lower eyelid
H11.31 Conjunctival hemorrhage, right eye
H52.6 Other disorders of refraction
H50.51 Esophoria
H02.055 Trichiasis without entropian left lower eyelid
H47.099 Other disorders of optic nerve, not elsewhere classified, unspecified eye
F51.8 Other sleep disorders not due to a substance or known physiological condition
G40.901 Epilepsy, unspecified, not intractable, with status epilepticus
L0881 Pyoderma vegetans
B009 Herpesviral infection, unspecified
J069 Acute upper respiratory infection, unspecified
M79.1 Myalgia
M12.39 Palindromic rheumatism, multiple sites
2016
E780 Pure hypercholesterolemia
G40.909 Epilepsy, unspecified, not intractable, without status epilepticus
L301 Dyshidrosis [pompholyx]
F32.9 Major depressive disorder, single episode, unspecified
D33.2 Benign neoplasm of brain, unspecified
H04.123 Dry eye syndrome of bilateral lacrimal glands
H47.529 Disorders of visual pathways in (due to) neoplasm, unspecified side
H02.052 Trichiasis without entropian right lower eyelid
H11.31 Conjunctival hemorrhage, right eye
H52.6 Other disorders of refraction
H50.51 Esophoria
H02.055 Trichiasis without entropian left lower eyelid
H47.099 Other disorders of optic nerve, not elsewhere classified, unspecified eye
F51.8 Other sleep disorders not due to a substance or known physiological condition
G40.901 Epilepsy, unspecified, not intractable, with status epilepticus
L0881 Pyoderma vegetans
B009 Herpesviral infection, unspecified
J069 Acute upper respiratory infection, unspecified
M79.1 Myalgia
M12.39 Palindromic rheumatism, multiple sites
Current treatment centers:
GP/ The department of Neurosurgical emergency & Critical Care of Chang Gung Memorial Hospital Linkou Branch/ TCM oncology of China Medical University Hospital Cancer Center/ and Taichung Hospital, Ministry of Health and Welfare
Contents of reference sources:
MIMS- Search drug information/ interaction/ images & medical diagnosis.
Complementary and Alternative Healing University- Dictionary of Chinese Herbs. http://alternativehealing.org
Database 醫砭‧沈藥子 http://yibian.hopto.org
Traditional Chinese Medicine (TCM) Wiki http://www.tcmwiki.com/
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